CHEMBL3966842


SMILES O=S(=O)(N[C@H]1CC[C@H](CCN2CCN(c3nsc4ccccc34)CC2)CC1)c1cccs1
InChIKey UCRMCTXHTPNGTQ-WGSAOQKQSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 490.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.48 8.71 8.96 ChEMBL
D3 DRD3 Human Dopamine A pKi 10.37 10.37 10.37 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.08 9.34 9.52 ChEMBL
D2 DRD2 Human Dopamine A pKi 9.37 9.37 9.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database