CHEMBL3965773


SMILES CN1CCc2ccc(OCCCN3CCN(c4cccc5sccc45)CC3)cc2C1=O
InChIKey RDOLSJCBVSDISX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 435.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Rat Histamine A pKi 6.86 6.86 6.86 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.53 8.34 9.15 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.19 7.19 7.19 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.82 7.82 7.82 ChEMBL
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 6.24 6.24 6.24 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database