CHEMBL3953773


SMILES CN(C(=O)N[C@H]1CC[C@H](CCN2CCN(c3nsc4ccccc34)CC2)CC1)c1ccccc1
InChIKey DKLFJXNMKAKPTA-HZCBDIJESA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 477.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.28 8.31 8.34 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.92 8.92 8.92 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.63 9.05 9.46 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.62 8.77 8.84 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database