CHEMBL3942236


SMILES O=C(c1ccco1)N1CCC(CCN2CCN(c3nsc4ccccc34)CC2)CC1
InChIKey DGSJCQBCZUXHPR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 424.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.14 9.14 9.14 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.14 8.14 8.14 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.66 8.66 8.66 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.82 7.82 7.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database