CHEMBL3929237


SMILES O=C1NCCc2ccc(OCCCN3CCN(c4cccc5sccc45)CC3)cc21
InChIKey ZCVYWZZKFYUXJC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 421.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 8.92 8.92 8.92 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.45 7.45 7.45 ChEMBL
H1 HRH1 Rat Histamine A pKi 6.86 6.86 6.86 ChEMBL
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 6.3 6.3 6.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database