dimaprit


SMILES CN(CCCSC(=N)N)C
InChIKey OLHQOJYVQUNWPL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 161.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pKi 6.1 6.1 6.1 Guide to Pharmacology
H4 HRH4 Human Histamine A pKi 4.9 5.7 6.5 Guide to Pharmacology
H2 HRH2 Guinea pig Histamine A pKd 4.58 4.58 4.58 ChEMBL
H4 HRH4 Human Histamine A pKi 6.5 6.64 7.05 ChEMBL
H2 HRH2 Human Histamine A pKi 4.6 4.6 4.6 ChEMBL
H3 HRH3 Guinea pig Histamine A pKi 7.32 7.32 7.32 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pEC50 5.8 5.8 5.8 ChEMBL