CHEMBL3918755


SMILES O=C(Nc1ccccc1)N[C@H]1CC[C@H](CCN2CCN(c3nsc4ccccc34)CC2)CC1
InChIKey LBCLWNAKMLUAKD-AQYVVDRMSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 463.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.44 8.64 8.85 ChEMBL
D3 DRD3 Human Dopamine A pKi 10.37 10.37 10.37 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.08 9.38 9.68 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.97 9.05 9.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database