CHEMBL3896937


SMILES O=C(Nc1cccnc1)N[C@H]1CC[C@H](CCN2CCN(c3nsc4ccccc34)CC2)CC1
InChIKey DBRVEHQLZZEVFX-MXVIHJGJSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 464.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.92 8.34 8.75 ChEMBL
D3 DRD3 Human Dopamine A pKi 10.26 10.26 10.26 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.31 9.58 9.85 ChEMBL
D2 DRD2 Human Dopamine A pKi 9.06 9.14 9.29 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database