dextromethorphan


SMILES COc1ccc2c(c1)[C@@]13CCCC[C@@H]3[C@H](C2)N(CC1)C
InChIKey MKXZASYAUGDDCJ-NJAFHUGGSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 1
Molecular weight (Da) 271.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MRGPRX2 MRGX2 Human Orphan A pEC50 5.23 5.36 5.49 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 4.75 5.08 5.4 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 8.2 8.2 8.2 ChEMBL
TAS2R46 T2R46 Human Taste 2 T2 pEC50 8.35 8.35 8.35 Drug Central
TAS2R46 T2R46 Human Taste 2 T2 pEC50 4.51 4.51 4.51 ChEMBL