CHEMBL1194252


SMILES O=C(NCCN1CCN(c2ncccn2)CC1)C12C[C@H]3C[C@@H](C1)C[C@@H](C2)C3
InChIKey HPFLVTSWRFCPCV-IVRKQUHDSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 369.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 6.78 6.78 6.78 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 9.0 9.0 9.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 5.9 5.9 5.9 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 8.68 8.68 8.68 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 7.47 7.47 7.47 ChEMBL