APLYSAMINE


SMILES CN(C)CCCOc1c(Br)cc(CCN(C)C)cc1Br
InChIKey LWENJEAGCYZOBC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 406.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 6.6 6.6 6.6 ChEMBL
H3 HRH3 Human Histamine A pKi 7.52 7.52 7.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Guinea pig Histamine A pIC50 6.3 6.3 6.3 ChEMBL