CHEMBL376414


SMILES Cc1ccc([C@H](Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C(C)(C)C)o1
InChIKey MYFOCPUZNAPZSE-NRFANRHFSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 6
Molecular weight (Da) 425.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR7 CCR7 Human Chemokine A pKi 7.44 7.59 7.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR7 CCR7 Human Chemokine A pIC50 5.89 6.17 6.46 ChEMBL
CXCR1 CXCR1 Human Chemokine A pIC50 7.96 7.96 7.96 ChEMBL
CXCR2 CXCR2 Human Chemokine A pIC50 8.42 8.42 8.42 ChEMBL