dAVP


SMILES NC(=O)CC1NC(=O)C(CCC(=O)N)NC(=O)C(Cc2ccccc2)NC(=O)C(NC(=O)CCSSCC(NC1=O)C(=O)N1CCCC1C(=O)NC(C(=O)NCC(=O)N)CCCN=C(N)N)Cc1ccc(cc1)O
InChIKey NFLWUMRGJYTJIN-UHFFFAOYSA-N
Sequence XYFQNCPRG

Chemical properties

Hydrogen bond acceptors 15
Hydrogen bond donors 13
Rotatable bonds 19
Molecular weight (Da) 1068.4

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
V1A V1AR Human Vasopressin and oxytocin A pKi 7.0 7.88 7.7 Guide to Pharmacology
V1B V1BR Human Vasopressin and oxytocin A pKi 7.7 8.38 9.4 Guide to Pharmacology
V2 V2R Human Vasopressin and oxytocin A pKi 7.2 8.1 8.6 Guide to Pharmacology
OT OXYR Human Vasopressin and oxytocin A pKi 6.7 7.73 7.6 Guide to Pharmacology
V1B V1BR Rat Vasopressin and oxytocin A pKi 8.0 8.0 8.0 Guide to Pharmacology
V2 V2R Rat Vasopressin and oxytocin A pKi 8.7 8.7 8.7 Guide to Pharmacology
V1A V1AR Rat Vasopressin and oxytocin A pKi 5.6 5.6 5.6 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database