CHEMBL3704623


SMILES O=C(O)CN1CCC[C@H]1Cc1nc2ccccc2n1[C@@H]1C[C@@H]2CCC[C@H](C1)N2[C@H]1C[C@H]2CCCC[C@H](C2)C1
InChIKey COWMKSSPBCWJGG-JBFJIUAJSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 518.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.31 7.54 7.77 ChEMBL
δ OPRD Human Opioid A pKi 4.7 4.7 4.7 ChEMBL
κ OPRK Human Opioid A pKi 6.46 6.53 6.59 ChEMBL
μ OPRM Human Opioid A pKi 5.4 5.47 5.55 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database