cyamemazine


SMILES N#Cc1ccc2c(c1)N(CC(CN(C)C)C)c1c(S2)cccc1
InChIKey SLFGIOIONGJGRT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 323.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.3 6.3 6.3 Guide to Pharmacology
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.8 8.8 8.8 Guide to Pharmacology
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.9 7.9 7.9 Guide to Pharmacology
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.2 7.2 7.2 Guide to Pharmacology
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.2 8.2 8.2 Drug Central
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.06 8.06 8.06 Drug Central
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.1 8.1 8.1 Drug Central
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.14 8.14 8.14 Drug Central
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.1 8.1 8.1 Drug Central
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 8.13 8.13 8.13 Drug Central
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 8.13 8.13 8.13 Drug Central
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.1 8.1 8.1 Drug Central
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 8.13 8.13 8.13 Drug Central
D1 DRD1 Human Dopamine A pKi 8.07 8.07 8.07 Drug Central
D2 DRD2 Human Dopamine A pKi 8.08 8.08 8.08 Drug Central
D3 DRD3 Human Dopamine A pKi 8.07 8.07 8.07 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database