CHEMBL3676929


SMILES O=C(N[C@H]1CC[C@H](CCN2CCC(c3coc4ccccc34)CC2)CC1)c1ccc(C2CC2)cc1
InChIKey JPCGHQPCQSFZIF-MGFGWZDJSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 470.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 7.85 7.85 7.85 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.67 8.67 8.67 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.45 6.45 6.45 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database