CHEMBL3676904


SMILES O=C(N[C@H]1CC[C@H](CCN2CCC(c3coc4ccccc34)CC2)CC1)c1ccc(-n2cccn2)cc1
InChIKey ONXKQTHNJXTCGP-OJBMAJLDSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 496.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 8.24 8.24 8.24 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.65 7.65 7.65 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.33 7.33 7.33 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database