CHEMBL3642790


SMILES COC(CCC(=O)N[C@H]1CC[C@H](CCN2CCN(c3nccc4c3CCO4)CC2)CC1)OC
InChIKey LIWZXUWAEHOPHY-MXVIHJGJSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 460.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 7.17 7.17 7.17 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.74 7.74 7.74 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.63 5.63 5.63 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database