CHEMBL3642777


SMILES CC(=O)N[C@H]1CC[C@H](CCN2CCN(c3nc(C)cc4c3CCO4)CC2)CC1
InChIKey VLMVFBMJXRVZOG-WGSAOQKQSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 386.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 8.12 8.12 8.12 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.67 6.67 6.67 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.04 6.04 6.04 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database