CHEMBL1171936


SMILES O=C(c1ccc(Oc2ccc(Cl)c(Cl)c2)nc1)N1CCCN(C2CCC2)CC1
InChIKey HMNMEBGQBBJDKL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 419.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 8.0 8.0 8.0 ChEMBL
H3 HRH3 Rat Histamine A pKd 8.16 8.16 8.16 ChEMBL
H3 HRH3 Human Histamine A pKd 9.26 9.26 9.26 ChEMBL
H3 HRH3 Human Histamine A pKi 8.12 8.12 8.12 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database