CHEMBL1170790


SMILES O=C(c1ccc(Oc2cccc(F)c2)nc1)N1CCCN(C2CCC2)CC1
InChIKey TYYPWLNLMMRCKN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 369.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 7.68 7.68 7.68 ChEMBL
H3 HRH3 Rat Histamine A pKd 8.38 8.38 8.38 ChEMBL
H3 HRH3 Human Histamine A pKi 8.39 8.39 8.39 ChEMBL
H3 HRH3 Human Histamine A pKd 9.4 9.4 9.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database