CP734432
| SMILES | O[C@@H](Cc1cccc(c1)C(F)(F)F)CC[C@H]1CCC(=O)N1CCCc1ccc(s1)C(=O)[O-] |
| InChIKey | JYZXGURJKNAFPT-ZWKOTPCHSA-M |
Chemical properties
| Hydrogen bond acceptors | 5 |
| Hydrogen bond donors | 1 |
| Rotatable bonds | 10 |
| Molecular weight (Da) | 468.1 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| EP4 | PE2R4 | Human | Prostanoid | A | pKi | 8.7 | 8.7 | 8.7 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| EP4 | PE2R4 | Human | Prostanoid | A | pEC50 | 9.0 | 9.0 | 9.0 | Guide to Pharmacology |
| EP4 | PE2R4 | Human | Prostanoid | A | pIC50 | 8.7 | 8.7 | 8.7 | Guide to Pharmacology |
| EP4 | PE2R4 | Rat | Prostanoid | A | pIC50 | 8.22 | 8.22 | 8.22 | ChEMBL |
| EP4 | PE2R4 | Rat | Prostanoid | A | pEC50 | 9.3 | 9.3 | 9.3 | ChEMBL |
| EP4 | PE2R4 | Human | Prostanoid | A | pIC50 | 8.7 | 8.7 | 8.7 | ChEMBL |
| EP2 | PE2R2 | Rat | Prostanoid | A | pIC50 | 6.32 | 6.32 | 6.32 | ChEMBL |