CHEMBL3609160


SMILES OCCN1CCN(c2nc(Nc3ccc(Br)cc3)c3ccccc3n2)CC1
InChIKey FVURRBVVEFEGAB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 427.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 6.24 6.24 6.24 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.04 7.04 7.04 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 4.56 4.56 4.56 ChEMBL