CHEMBL3310783


SMILES N#Cc1c(O)nc(SCc2cccc(F)c2F)nc1C1CC1
InChIKey PHHZYKZFEBRXAL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 319.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.18 5.18 5.18 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CX3CR1 CX3C1 Human Chemokine A pEC50 5.85 5.85 5.85 ChEMBL
CXCR2 CXCR2 Human Chemokine A pIC50 6.85 7.12 7.4 ChEMBL