CHEMBL3085826


SMILES CN(C)C(=O)N[C@H]1CC[C@@H](CCN2CCN(c3cccc(Cl)c3Cl)CC2)CC1
InChIKey KPWSJANDNDDRMB-CALCHBBNSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 426.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 6.99 8.05 9.11 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.67 8.67 8.67 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.69 7.69 7.69 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pEC50 7.92 8.21 8.52 ChEMBL