CHEMBL285157


SMILES C1=C(c2c[nH]c3ccccc23)CCN(Cc2ccccc2)C1
InChIKey TYKXLUMYKFFSJE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 288.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.03 6.04 6.04 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.45 6.45 6.45 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.9 6.9 6.9 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.59 7.59 7.59 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 5.58 5.58 5.58 ChEMBL