VANOXERINE


SMILES Fc1ccc(C(OCCN2CCN(CCCc3ccccc3)CC2)c2ccc(F)cc2)cc1
InChIKey NAUWTFJOPJWYOT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight (Da) 450.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 5.1 5.45 5.8 ChEMBL
NPS NPSR1 Human Neuropeptide S A Potency 4.9 4.9 4.9 ChEMBL
κ OPRK Human Opioid A pIC50 5.67 5.67 5.67 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 4.4 4.8 5.2 ChEMBL
μ OPRM Human Opioid A pIC50 5.45 5.45 5.45 ChEMBL