MECOPROP


SMILES Cc1cc(Cl)ccc1OC(C)C(=O)O
InChIKey WNTGYJSOUMFZEP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 214.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Ligand site mutations 5-HT2C

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 7.03 7.03 7.03 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 6.92 6.92 6.92 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 6.82 6.82 6.82 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 5.2 5.2 5.2 ChEMBL