MGCD-265


SMILES Cn1cnc(-c2cc3nccc(Oc4ccc(NC(=S)NC(=O)Cc5ccccc5)cc4F)c3s2)c1
InChIKey UFICVEHDQUKCEA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 517.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SMO SMO Human Oxysterol F pKi 7.28 7.33 7.38 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FPR3 FPR3 Human Formylpeptide A pIC50 5.61 5.61 5.61 ChEMBL
GPR183 GP183 Human Orphan A pIC50 5.7 5.7 5.7 ChEMBL
GPR35 GPR35 Human Orphan A pIC50 5.37 5.37 5.37 ChEMBL
FPR1 FPR1 Human Formylpeptide A pIC50 5.36 5.36 5.36 ChEMBL