REMOXIPRIDE


SMILES CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC
InChIKey GUJRSXAPGDDABA-NSHDSACASA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 370.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Green monkey Dopamine A pKi 5.34 5.34 5.34 ChEMBL
D2 DRD2 Green monkey Dopamine A pKi 6.06 6.06 6.06 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.41 5.41 5.41 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKd 5.4 5.4 5.4 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKd 8.27 8.27 8.27 Drug Central
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.26 8.26 8.26 Drug Central
D3 DRD3 Human Dopamine A pKi 8.15 8.15 8.15 Drug Central
D4 DRD4 Human Dopamine A pKi 8.27 8.27 8.27 Drug Central
D2 DRD2 Green monkey Dopamine A pKi 8.22 8.22 8.22 Drug Central
D3 DRD3 Green monkey Dopamine A pKi 8.27 8.27 8.27 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pIC50 5.8 5.82 5.85 ChEMBL
D4 DRD4 Human Dopamine A pIC50 5.41 5.41 5.41 ChEMBL
D2 DRD2 Human Dopamine A pIC50 6.06 7.49 8.92 ChEMBL
D2 DRD2 Human Dopamine A pIC50 8.22 8.22 8.22 Drug Central
D2 DRD2 Rat Dopamine A pIC50 8.23 8.23 8.23 Drug Central