CLOPROSTENOL


SMILES O=C(O)CCC/C=C\CC1C(O)CC(O)C1/C=C/C(O)COc1cccc(Cl)c1
InChIKey VJGGHXVGBSZVMZ-YVKATYTESA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 11
Molecular weight (Da) 424.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FP PF2R Human Prostanoid A pKi 7.51 7.51 7.51 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP1 PE2R1 Human Prostanoid A pIC50 6.3 6.3 6.3 ChEMBL
EP1 PE2R1 Human Prostanoid A pEC50 6.12 6.12 6.12 ChEMBL
FP PF2R Human Prostanoid A pIC50 8.7 8.85 9.0 ChEMBL
FP PF2R Human Prostanoid A pEC50 8.0 8.0 8.0 ChEMBL
EP3 PE2R3 Human Prostanoid A pIC50 6.2 6.2 6.2 ChEMBL
EP3 PE2R3 Human Prostanoid A pEC50 5.3 5.3 5.3 ChEMBL
EP2 PE2R2 Human Prostanoid A pIC50 5.43 5.43 5.43 ChEMBL
TP TA2R Human Prostanoid A pEC50 5.62 5.62 5.62 ChEMBL