CHEMBL2181247


SMILES O=C1COc2nccc(-c3ccccc3F)c2CN1Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1
InChIKey ZIXNJVGTAXRKAP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 484.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR183 GP183 Human Orphan A pIC50 5.38 5.38 5.38 ChEMBL
GPBA GPBAR Mouse Bile acid A pEC50 6.89 6.89 6.89 ChEMBL
GPR35 GPR35 Human Orphan A pIC50 5.22 5.22 5.22 ChEMBL
GPBA GPBAR Human Bile acid A pEC50 7.72 8.68 9.64 ChEMBL
β2 ADRB2 Human Adrenoceptors A pIC50 5.82 5.82 5.82 ChEMBL
apelin APJ Human Apelin A pIC50 5.8 5.8 5.8 ChEMBL
GLP-1 GLP1R Human Glucagon B1 pIC50 5.61 5.61 5.61 ChEMBL
FPR1 FPR1 Human Formylpeptide A pIC50 5.61 5.61 5.61 ChEMBL