CHEMBL2165117


SMILES O=C1NCCc2ccc(OCCCN3CCN(c4cccc(Cl)c4Cl)CC3)cc21
InChIKey QXPBZNWEPREKHB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 433.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.84 7.84 7.84 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.67 7.72 7.75 ChEMBL
H1 HRH1 Rat Histamine A pKi 7.05 7.05 7.05 ChEMBL
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 6.59 6.59 6.59 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pEC50 7.52 7.61 7.7 ChEMBL