CHEMBL2158418


SMILES COc1cc([C@H]2[C@](NC(=O)c3ccc(NC(=O)C4CCCC4)cc3)(C(=O)O)[C@@H](c3ccc(OC(=O)c4cccs4)c(OC)c3)[C@@]2(NC(=O)c2ccc(NC(=O)C3CCCC3)cc2)C(=O)O)ccc1OC(=O)c1cccs1
InChIKey NEGLAHVNMIDVPL-BLDBZDEWSA-N

Chemical properties

Hydrogen bond acceptors 14
Hydrogen bond donors 6
Rotatable bonds 18
Molecular weight (Da) 1068.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GLP-1 GLP1R Rat Glucagon B1 pKi 6.54 6.54 6.54 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GLP-1 GLP1R Rat Glucagon B1 pEC50 5.97 6.07 6.18 ChEMBL
GLP-1 GLP1R Rat Glucagon B1 pIC50 6.52 6.52 6.52 ChEMBL