CHEMBL2036650


SMILES C[C@@H]1CCCN1CCCOc1ccc(C(=O)CN2CCN(C(=O)c3ccco3)CC2)cc1
InChIKey TXUQRJZCUVIQAO-HXUWFJFHSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 439.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 7.8 7.8 7.8 ChEMBL
H3 HRH3 Human Histamine A pKi 8.7 8.7 8.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database