CHEMBL200382


SMILES O=C(CCN1CCC(Cc2c[nH]cn2)CC1)Nc1cccc(F)c1
InChIKey XYJMAXNKTLJWRH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 330.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Guinea pig Histamine A pKd 9.9 9.9 9.9 ChEMBL
H3 HRH3 Guinea pig Histamine A pKi 9.7 9.7 9.7 ChEMBL
H3 HRH3 Human Histamine A pKi 8.72 8.72 8.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database