CHEMBL1962947


SMILES COc1cc2c(cc1O)CN1CCc3cc(OC)c(O)cc3[C@@H]1C2
InChIKey FQPSOJRHFJUUMC-HNNXBMFYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 327.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 7.98 7.98 7.98 ChEMBL
D1 DRD1 Human Dopamine A pKi 8.24 8.24 8.24 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.26 6.26 6.26 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.29 6.54 6.78 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pEC50 8.25 8.25 8.25 ChEMBL
D2 DRD2 Human Dopamine A pEC50 4.25 4.25 4.25 ChEMBL