CHEMBL1938952


SMILES COc1ccncc1C(=O)NC(=O)Nc1ccc(-c2ccccc2)c(C(F)(F)F)c1
InChIKey MLDQTQOMWDNTNN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 415.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR183 GP183 Human Orphan A pIC50 5.36 5.36 5.36 ChEMBL
S1P1 S1PR1 Human Lysophospholipid (S1P) A pEC50 7.46 7.64 8.0 ChEMBL
β2 ADRB2 Human Adrenoceptors A pIC50 5.31 5.31 5.31 ChEMBL
apelin APJ Human Apelin A pIC50 5.07 5.07 5.07 ChEMBL
S1P5 S1PR5 Human Lysophospholipid (S1P) A pEC50 5.37 5.37 5.37 ChEMBL