CHEMBL1773087


SMILES CN(CCC(F)CN1CCN(c2cccc(Cl)c2Cl)CC1)Cc1ccc2c(c1)Cc1ccccc1-2
InChIKey KROSHEKWTTXFGB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 511.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 6.41 6.41 6.41 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.59 5.59 5.59 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.69 5.69 5.69 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pIC50 6.04 6.04 6.04 ChEMBL