AZ2158


SMILES CO[C@H]1CCC(CC1)N2N=C(C)C(C(=O)N[C@@H](C)C(C)(C)C)=C2NS(=O)(=O)C3=CC=C(C)C=C3
InChIKey NDFKHRWYNVKHBS-WMEOFMBSSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 490.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FPR1 FPR1 Human Formylpeptide A pKd 7.7 7.7 7.7 Guide to Pharmacology
FPR1 FPR1 Human Formylpeptide A pKd 7.7 7.7 7.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FPR1 FPR1 Human Formylpeptide A pIC50 8.4 8.4 8.4 ChEMBL