atoxifent


SMILES OC1=CC(N2[C@H]3CC[C@@H]2CN(CCCC4=CC=CC=C4)C3)=CC=C1
InChIKey PEXKBSSCTUNEBX-BGYRXZFFSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 322.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 8.66 8.66 8.66 Guide to Pharmacology
μ OPRM Human Opioid A pEC50 9.41 9.41 9.41 Guide to Pharmacology
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 5.95 5.95 5.95 ChEMBL
δ OPRD Human Opioid A pEC50 8.35 8.5 8.66 ChEMBL
μ OPRM Human Opioid A pEC50 8.78 9.09 9.41 ChEMBL
α1A ADA1A Human Adrenoceptors A pIC50 5.06 5.06 5.06 ChEMBL
α2A ADA2A Human Adrenoceptors A pIC50 5.26 5.26 5.26 ChEMBL
κ OPRK Human Opioid A pIC50 5.68 6.06 6.45 ChEMBL