Structure information

HCA3 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

9JKS

SPECIES

Homo sapiens

RESOLUTION

3.310

PREFERRED CHAIN

A

REFERENCE

PUBLICATION DATE

Oct. 29, 2025

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
compound 6o [PMID: 19524438] V83 2.60x60 TM2 hydrophobic
compound 6o [PMID: 19524438] Y86 2.63x63 TM2 hydrophobic
compound 6o [PMID: 19524438] F107 3.32x32 TM3 hydrophobic
compound 6o [PMID: 19524438] S179 45.52x52 ECL2 polar (hydrogen bond)
compound 6o [PMID: 19524438] S179 45.52x52 ECL2 Van der Waals
compound 6o [PMID: 19524438] F180 ECL2 Van der Waals
compound 6o [PMID: 19524438] F277 7.36x35 TM7 aromatic (edge-to-face)
compound 6o [PMID: 19524438] F277 7.36x35 TM7 Van der Waals
compound 6o [PMID: 19524438] L280 7.39x38 TM7 Van der Waals
compound 6o [PMID: 19524438] L280 7.39x38 TM7 hydrophobic
compound 6o [PMID: 19524438] Y284 7.43x42 TM7 polar (hydrogen bond)

Ligands

compound 6o [PMID: 19524438]

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Residue Diagrams

G N G L L G F I F E L G L V P P L V K A 1 F N L A V A D F L L I I C L P F V M D Y 2 V T L F I I S G Q R N M A F M F L V L R 3 A A I I S C L L W G I T V G L T V H L L 4 S C F L I I G L P L F F E L L F M A E H W 5 M V V A I V F V I C F L P S V V V R I H 6 V P D L M S N M Y T F S L T I F F A L 7
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ICL1 L K S W ICL1ECL1 R S D W K F ECL1ICL2 P H H A L N K I ICL2ECL2 L L I Q N G T A N V C I S F S I C H T F ECL2ICL3 Q M D R H A ICL3ECL3 G T Q N C E ECL3N-term M N R H H L Q D H F L E I D K K N C C V F R N-termC-term R C L Q R K I T G E P D N N R S T S V E L T G D P N K T R G A P E A L I A N S G E P W S P S Y L G P T S N N H S K K G H C H Q E P A S L E K Q L G C C I E C-term D D F I A K V L P P V L G L E F I F G L L G N G L A L W I F C F H K S S R I F L F N L A V A D F L L I I C L P F V M D Y Y V R G D I P C R L V L F M F A M N R Q G S I I F L T V V A V D R Y F R V V H S N W T A A I I S C L L W G I T V G L T V H L L K K K R W H E A M F L L E F F L P L G I I L F C S A R I I W S L R Q R K I K R A I T F I M V V A I V F V I C F L P S V V V R I H I F W L L H T S V Y R S V D L A F F I T L S F T Y M N S M L D P V V Y Y F S S P S F S T F P N F L I N
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Residue Table


GPCRdb(A)
GPCRdb(A)
HCA3 receptor
TM2
2x60 2.60x60 V83
2x63 2.63x63 Y86
TM3
3x32 3.32x32 F107
ECL2
45x52 45.52x52 S179
TM7
7x35 7.36x35 F277
7x38 7.39x38 L280
7x42 7.43x42 Y284