Structure information

CX3CR1

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

7XBX

SPECIES

Homo sapiens

RESOLUTION

3.400

PREFERRED CHAIN

R

REFERENCE

PUBLICATION DATE

July 13, 2022

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
Cholesterol F314 5.59x59 TM5 hydrophobic
Cholesterol I317 5.62x62 TM5 hydrophobic
Cholesterol F321 5.66x66 TM5 polar (hydrogen bond)

Ligands

Cholesterol

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Residue Diagrams

L N G V L G I A F I V S Y F I S L F V T 1 L N L A L S D L L F V A T L P F W T H Y 2 V T I F F I S G F F G I F F F A T T F K 3 G V T I S L G V W A A A I L V A A P Q 4 Y C Y S M I L L P L L F G L F N T E V N R 5 L L V V I V F F L F W T P Y N V M I F L 6 L P N L C C H S F A V T E T V S L A L 7
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ICL1 K K P K ICL1ECL1 E K G L H N A ECL1ICL2 A A N S M N N R ICL2ECL2 K Q K E N E C L G D Y P E V ECL2ICL3 K N ICL3ECL3 F F P ECL3N-term M D Q F P E S V T E N F E Y D D L A E A C Y N-termC-term C L A V L C G R S V H V D F S S S E S Q R S R H G S V L S S N F T Y H T S D G D A L L L L C-term I G D I V V F G T V F L S I F Y S V I F A I G L V G N L L V V F A L T N S S V T D I Y L L N L A L S D L L F V A T L P F W T H Y L I N M C K F T T A F F F I G F F G S I F F I T V I S I D R Y L A I V L T V Q H G V T I S L G V W A A A I L V A A P Q F M F T L Q E I W P V L R N V E T N F L G F L L P L L I M S Y C Y F R I I Q T L F S C H K K A K A I K L I L L V V I V F F L F W T P Y N V M I F L E T L K L Y D S C D M R K D L R L A L S V T E T V A F S H C C L N P L I Y A F A G E K L Y H F R R Y L Y G K
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Residue Table


GPCRdb(A)
GPCRdb(A)
CX3CR1
TM5
5x59 5.59x59 F212
5x62 5.62x62 I215
5x66 5.66x66 F219