Structure information

ADGRF1

PROTEIN CLASS

Class B2 (Adhesion)

PDB CODE

7WU4

SPECIES

Homo sapiens

RESOLUTION

3.400

PREFERRED CHAIN

R

REFERENCE

10.1038/S41586-022-04580-W

PUBLICATION DATE

April 27, 2022

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
LPC 16:0 W674 3.46x46 TM3 hydrophobic
LPC 16:0 M677 3.49x49 TM3 hydrophobic
LPC 16:0 I680 3.52x52 TM3 hydrophobic
LPC 16:0 L681 3.53x53 TM3 hydrophobic
LPC 16:0 Y684 3.56x56 TM3 hydrophobic
LPC 16:0 M698 4.41x42 TM4 hydrophobic
LPC 16:0 M699 4.42x43 TM4 hydrophobic

Ligands

LPC 16:0

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Residue Diagrams

I L S G I S I G L G V Y T I W K V V P F 1 V N I A L S L L I A D V W F I V G A T V 2 M L M W F F L S L Y F F H T F F V A A T 3 M M A V G F C G L Y G C P L I I S V I T I 4 V V V F N V A V I A L A P V V F A L L P 5 L I L T P L L G L T W G F G I G T I V D 6 C L I F F G Q F A N L L A F I V H W A 7
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ICL1 K Q I K K ICL1ECL1 D T T V N P ECL1ICL2 V F H H M ICL2ECL2 P S N T Y K R K D V C W L N W S N G S ECL2ICL3 P T V G E R L S R ICL3ECL3 Q ECL3N-term M K V G V L W L I S F F T F T D G H G G F L G K N D G I K T K K E L I V N K K K H L G P V E E Y Q L L L Q V T Y R D S K E K R D L R N F L K L L K P P L L W S H G L I R I I R A K A T T D C N S L N G V L Q C T C E D S Y T W F P P S C L D P Q N C Y L H T A G A L P S C E C H L N N L S Q S V N F C E R T K I W G T F K I N E R F T N D L L N S S S A I Y S K Y A N G I E I Q L K K A Y E R I Q G F E S V Q V T Q F R N G S I V A G Y E V V G S S S A S E L L S A I E H V A E K A K T A L H K L F P L E D G S F R V F G K A Q C N D I V F G F G S K D D E Y T L P C S S G Y R G N I T A K C E S S G W Q V I R E T C V L N-termC-term W K Q T E K Q N S S D L S A K P K F S K P F N P L Q N K G H Y A F S H T G D S S D N I M L T Q F V S N E C-term P S T I F P V V K W I T Y V G L G I S I G S L I L C L I I E A L F W S Q T S H T R R I C M V N I A L S L L I A D V W F I V G A T V S G V C T A A V F F T H F F Y L S L F F W M L M L G I L L A Y R I I L A Q H L M M A V G F C L G Y G C P L I I S V I T I A V T Q K P L L A F V V P A L A I V A V N F V V V L L V L T K L W R D D K A T I I R V G K S L L I L T P L L G L T W G F G I G T I V D S N L A W H V I F A L L N A F Q G F F I L C F G I L L D S K L F N L S S L R Q L K L S A
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Residue Table


GPCRdb(A)
GPCRdb(B)
ADGRF1
TM3
3x42 3.46x46 W674
3x45 3.49x49 M677
3x48 3.52x52 I680
3x49 3.53x53 L681
3x52 3.56x56 Y684
TM4
4x42 4.41x42 M698
4x43 4.42x43 M699