Structure information

μ receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

10TM

SPECIES

Homo sapiens

RESOLUTION

3.000

PREFERRED CHAIN

F

REFERENCE

PUBLICATION DATE

May 27, 2026

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
DAMGO W135 23.50x50 ECL1 hydrophobic
DAMGO V145 3.28x28 TM3 hydrophobic
DAMGO I146 3.29x29 TM3 hydrophobic
DAMGO C219 45.50x50 ECL2 hydrophobic
DAMGO V238 5.42x43 TM5 hydrophobic
DAMGO I298 6.51x51 TM6 hydrophobic
DAMGO V302 6.55x55 TM6 hydrophobic
DAMGO W320 7.35x34 TM7 hydrophobic
DAMGO I324 7.39x38 TM7 hydrophobic
DAMGO Y328 7.43x42 TM7 polar (hydrogen bond)

Ligands

DAMGO

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Residue Diagrams

F N G F L G V V C V I S Y L A M I T I A 1 F N L A L A D A L A T S T L P F Q S V N 2 T C L T F I S T F M N Y Y D I S I V I K 3 A K I I N V C N W I L S S A I G L P V M 4 Y C V T I I L V P M I F A F I F V C I K L 5 L V V V A V F I V C W T P I H I Y V I I 6 V P N L C S N T Y G L A I C F H W S V 7
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ICL1 T K M K ICL1ECL1 T W P F ECL1ICL2 P V K A L D F R ICL2ECL2 T T K Y R Q G S I D C T L T F S H ECL2ICL3 R M L S G ICL3ECL3 T I P E ECL3N-term M D S S A A P T N A S N C T D A L A Y S S C S P A P S P G S W V N L S H L D G N L S D P C G P N R T D L G G R D S L C P P T G S P S N-termC-term P T S S N I E Q Q N S T R I R Q N T R D H P S T A N T V D R T N H Q L E N L E A E T A P L P C-term M I T A I T I M A L Y S I V C V V G L F G N F L V M Y V I V R Y T A T N I Y I F N L A L A D A L A T S T L P F Q S V N Y L M G G T I L C K I V I S I D Y Y N M F T S I F T L C T M S V D R Y I A V C H T P R N A K I I N V C N W I L S S A I G L P V M F M A P T W Y W E N L L K I C V F I F A F I M P V L I I T V C Y G L M I L R L K S V S K E K D R N L R R I T R M V L V V V A V F I V C W T P I H I Y V I I K A L V T T F Q T V S W H F C I A L G Y T N S C L N P V L Y A F L D E N F R E F K R C F C I
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Residue Table


GPCRdb(A)
GPCRdb(A)
μ receptor
ECL1
23x50 23.50x50 W135
TM3
3x28 3.28x28 V145
3x29 3.29x29 I146
ECL2
45x50 45.50x50 C219
TM5
5x43 5.42x43 V238
TM6
6x51 6.51x51 I298
6x55 6.55x55 V302
TM7
7x34 7.35x34 W320
7x38 7.39x38 I324
7x42 7.43x42 Y328